摘要 |
FIELD: medicine. ^ SUBSTANCE: invention relates to field of medicine and deals with anti-sense oligonucleotides for treatment and/or prevention of, at least, one of the following diseases: asthma, hypereosinophilia. Essence of the invention includes oligonucleotides aimed against sequences of nucleic acids, coding receptor, selected from group, which consists of receptor CCR3 and common subunit of receptors IL-3, IL-5 and GM-CSF with sequences SEQ ID NO:1 and SEQ ID NO:14. ^ EFFECT: reduction of toxicity in comparison with hormonal medications. ^ 39 cl, 8 ex, 11 tbl, 21 dwg |