PREPARATION METHOD OF SILK/HYDROXYAPATITE HYBRID NANOFIBER SCAFFOLD FOR BONE REGENERATION
摘要
PURPOSE: A manufacturing method of a silk/hydroxyapatite complex nanofiber supporter for osteanagenesis is provided to efficiently coat the silk nanofiber supporter with hydroxyapatite in a short time. CONSTITUTION: A manufacturing method of a silk/hydroxyapatite complex nanofiber supporter for osteanagenesis comprises: a step of preparing silk spinning undiluted solution; a step of electrospinning the silk spinning undiluted solution; a step of dispersing the spun silk nanofiber; a step of manufacturing silk nanofiber having a sponge shape by freeze-drying the dispersed silk nanofiber; a step of coating the silk nanofiber with hydroxyapatite by dipping the silk nanofiber in simulated body fluid; and a step of forming pores on the silk nanofiber coated with hydroxyapatite.
申请公布号
KR20110040389(A)
申请公布日期
2011.04.20
申请号
KR20090097627
申请日期
2009.10.14
申请人
SNU R&DB FOUNDATION;REPUBLIC OF KOREA(MANAGEMENT : RURAL DEVELOPMENT ADMINISTRATION)
发明人
PARK, YOUNG HWAN;KI, CHANG SEOK;LEE, MIN JUNG;KIM, JONG WOOK;LEE, KWANG GILL;KANG, SEOK WOO;KWEON, HAE YONG;YEO, JOO HONG;JO, YOU YOUNG