发明名称 |
Antibody directed against gastrin-releasing peptide precursor and use thereof |
摘要 |
Disclosed is a novel method for determination of ProGRP which is free from problems such as the dispersion in the values of measurements and operational constraints such as handling of a test sample. A method for the determination of a gastrin-releasing peptide precursor or a digest thereof using at least two different antibodies each of which can recognize a peptide comprising the partial amino acid sequence starting from amino acid residue 40 and ended at amino acid residue 75 in the amino acid sequence depicted in SEQ ID NO:1; and a method for the determination of a gastrin-releasing peptide precursor and/or a digest thereof using at least two different antibodies each of which can recognize a peptide comprising the partial amino acid sequence starting from amino acid residue 40 and ended at amino acid residue 79 in the amino acid sequence depicted in SEQ ID NO:1. The methods have such advantages that a detection sensitivity comparable to that in a conventional determination method can be achieved, that it is easy to handle a sample after the sample is collected, and that a highly reproducible measurements can be obtained.
|
申请公布号 |
US7927814(B2) |
申请公布日期 |
2011.04.19 |
申请号 |
US20070974820 |
申请日期 |
2007.10.15 |
申请人 |
ADVANCED LIFE SCIENCE INSTITUTE, INC. |
发明人 |
AOYAGI KATSUMI |
分类号 |
C12Q1/00;G01N33/00;G01N33/48;G01N33/53;G01N33/566;G01N33/567;G01N33/574 |
主分类号 |
C12Q1/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|