发明名称 |
P-toluene sulfonic acid salt of 5-amino-3-(2′-O-acetyl-3′-deoxy-β-D-ribofuranosyl)-3H-thiazole[4,5-d]pyrimidine-2-one and methods for preparation |
摘要 |
The present disclosure relates to p-toluene sulfonic acid salt of 5-amino-3-(2′-O-acetyl-3′-deoxy-beta-D-ribofuranosyl)-3H-thiazolo[4,5-d]pyrimidin-2-one and to its use in treating conditions such as viral infections, tumors, and cancer. Also disclosed is a method of preparing the p-toluene sulfonic acid salt of 5-amino-3-(2′-O-acetyl-3′-deoxy-&bgr;-D-ribofuranosyl)-3H-thiazolo[4,5-d]pyrimidin-2-one and methods for producing furanose compounds which are useful intermediates in the preparation of pharmaceutical compounds such as p-toluene sulfonic acid salt of 5-amino-3-(2′-O-acetyl-3′-deoxy-&bgr;-D-ribofuranosyl)-3H-thiazolo[4,5-d]pyrimidin-2-one and the like.
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申请公布号 |
US7928085(B2) |
申请公布日期 |
2011.04.19 |
申请号 |
US20070873202 |
申请日期 |
2007.10.16 |
申请人 |
ANADYS PHARMACEUTICALS, INC. |
发明人 |
KUCERA DAVID;HALEY GREGORY J.;RUEDEN ERIK J.;WANG TINGMIN;BLATTER FRITZ;VIERTELHAUS MARTIN |
分类号 |
C07H19/00;A01N43/04;A61K31/70 |
主分类号 |
C07H19/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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