发明名称 Methods for refolding of recombinant antibodies
摘要 The present invention is generally directed to methods of producing an increase in the enrichment or recovery of preferred forms of IgG proteins. More particularly, the invention relates to subjecting preparations of such recombinant IgG proteins with a reduction/oxidation coupling reagent and optionally a chaotropic agent.
申请公布号 US7928205(B2) 申请公布日期 2011.04.19
申请号 US20050255528 申请日期 2005.10.21
申请人 AMGEN INC. 发明人 DILLON THOMAS M.;REHDER DOUGLAS;BONDARENKO PAVEL;RICCI MARGARET;GADGIL HIMANSHU S.;BANKS DOUGLAS D.;ZHOU JOE;LU YUEFENG;GOETZE ANDREW;ZHANG YULING
分类号 A61K39/395;C07K16/00 主分类号 A61K39/395
代理机构 代理人
主权项
地址