发明名称 |
Förfarande för bestämning av kardiovaskulära händelser genom att använda IGFBP-fragment |
摘要 |
The present invention describes the method for determining the risk of future major adverse cardiovascular events, which comprises detection proteolytic fragments of IGFBP-4 or IGFBP-5 (insulin-like growth factor binding protein 4 or insulin-like growth factor binding protein 5) in patients' blood. The present invention provides antibodies and immunoas-says, suitable for specific measurement of proteolytic fragments of IGFBPs. In current invention the IGFBP fragments are suggested to be utilized as blood biomarkers for the risk prediction of major adverse cardiovascular events (MACE). |
申请公布号 |
FI20115367(A0) |
申请公布日期 |
2011.04.15 |
申请号 |
FI20110005367 |
申请日期 |
2011.04.15 |
申请人 |
HYTEST OY |
发明人 |
KATRUKHA, ALEXEY G.;POSTNIKOV, ALEXANDER B.;SOLOVYEVA, TATIANA I.;KHARITONOV, ALEXEY V. |
分类号 |
C07K |
主分类号 |
C07K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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