IN VIVO CHEMICAL STABILIZATION OF VULNERABLE PLAQUE
摘要
<p>Procedures for the stabilization of vulnerable plaque can comprise identification of the vulnerable plaque and the delivery of a stabilization composition to the location of the vulnerable plaque. For example, the stabilization composition can be delivered to an isolated portion of the vessel with the vulnerable plaque and/or alternatively or additionally using a profusion balloon that delivers the stabilization composition at the vessel wall near the vulnerable plaque. Suitable stabilization compositions can comprise a collagen crosslinking agent, an elastin stabilization agent, VEGF or a combination thereof. Vascular endothelial growth factor (VEGF) can be used to encourage endothelialization of the vessel wall near the vulnerable plaque.</p>
申请公布号
WO2011044455(A1)
申请公布日期
2011.04.14
申请号
WO2010US51968
申请日期
2010.10.08
申请人
VATRIX MEDICAL, INC.;OGLE, MATTHEW, F.;DIPPEL, ERIC, J.