UDP-GALACTOPYRANOSE MUTASE FROM HAEMONCHUS CONTORTUS, AND RNAI AGENTS THAT INHIBIT IT

摘要

The invention relates to the cloning of the Haemonchus contortus UDP-galactopyranose mutase gene, which is homologous to the C elegans glf-1. Also disclosed is the use of RNAi agents targeting this enzyme to treat or prevent a parasitic nematode infection, and the use of this enzyme to detect a nematode infection.