| 摘要 |
A substituted, high molecular weight product which forms a gel in water of limited swelling capacity is prepared by reacting swollen gel grains of a copolymerizate of a polyhydroxy compound with a bifunctional aliphatic compound which may be interrupted with ether groups and which contains halogen atoms or epoxy groups at the ends, with substances having the general formula X1-R1-Z in the presence of alkali, wherein X1 represents chlorine, bromine or a 1,2-epoxy ethylene group, R1 represents methylene or ethylene and Z represents the carboxyl or sulpho group or a salt thereof or a tertiary amino group of the formula <FORM:0936039/IV(a)/1> or salt thereof, wherein R2 and R3 are lower possibly hydroxyl group-substituted alkyl groups or lower alkylene groups which may be linked to form a 5 or 6 membered heterocyclic ring system. The polyhydroxy compound may be dextran, cellulose, hydroxyethyl cellulose, starch dextran, cellulose, hydroxyethyl cellulose, starch dextran, or sorbitol. The aliphatic compound may be epichlorohydrin, dichlorohydrin, diepoxybutane, bis-epoxypropylether, ethylene glycol-bis-epoxyprophylether, and 1,4-butanediolbis-epoxypropylether. These starting materials may be the polyhydroxyl compound-aliphatic compound reaction products described in Specification 854,715. Examples of the compounds X1-R1-Z are chloracetic acid, bromacetic acid, chloropropionic acid, chloromethane sulphonic acid, bromoethane p sulphonic acid, chloroethane sulphonic acid, 1-(diethylamino)-2,3-epoxypropane, diethylaminoethyl chloride, dimethylamino ethyl chloride, di-(hydroxyethyl)-amino ethyl chloride, and b -morpholinoethyl chloride. Reaction may be effected at 15 DEG -120 DEG C. using toluene as a solvent. The final products may be used as ion-exchangers. |
