发明名称 |
Low Temperature, Single Solvent Process for the Production of Sucrose-6-Ester |
摘要 |
A method for the preparation of a sucrose-6-ester is disclosed. In a first step of the method, sucrose in a polar aprotic solvent is reacted with an organotin-based acylation promoter. The water of reaction is removed at a temperature that does not exceed about 80° C. In one aspect, the water is removed by distillation of part of the polar aprotic solvent at reduced pressure. In a second step, a carboxylic acid anhydride is added. In one aspect, the resulting reaction mixture is maintained at a temperature of 10° C. or less for a period of time sufficient to produce a sucrose-6-ester. The sucrose-6-ester can be converted to sucralose.
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申请公布号 |
US2011087018(A1) |
申请公布日期 |
2011.04.14 |
申请号 |
US20100901808 |
申请日期 |
2010.10.11 |
申请人 |
TATE & LYLE TECHNOLOGY LIMITED |
发明人 |
MICINSKI EDWARD;COLEMAN DAVID;WILEY, JR. JAMES EDWIN |
分类号 |
C07H1/00 |
主分类号 |
C07H1/00 |
代理机构 |
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主权项 |
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地址 |
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