| 发明名称 |
ANTIBODIES AGAINST IL-13 RECEPTOR ALPHA 1 AND USES THEREOF |
| 摘要 |
An antibody binding to IL-13Rα1, inhibiting IL-13 bioactivity and comprising a variable heavy and a variable light chain, characterized in that the variable heavy chain amino acid sequence CDR3 of said antibody is selected from the group consisting of the heavy chain CDR3 sequences of SEQ ID NO: 1, 3, 5, 7 or 9 is useful in the treatment of asthma and allergic diseases.
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| 申请公布号 |
US2011086026(A1) |
申请公布日期 |
2011.04.14 |
| 申请号 |
US20100843225 |
申请日期 |
2010.07.26 |
| 申请人 |
ENDL JOSEF;FUENTES MARIA ELENA;GRAUS YVO;GROSSMANN ADELBERT;NEUMANN SEBASTIAN;PARREN PAUL;REBERS FRANK;REGULA JOERG THOMAS;SCHUMACHER RALF;SEEBER STEFAN;STRACKE JAN OLAF;STUBENRAUCH KAY-GUNNAR;VAN DE WINKEL JAN;VAN VUGT MARTINE;VEREECKEN-VERPLOEGEN SANDRA |
发明人 |
ENDL JOSEF;FUENTES MARIA ELENA;GRAUS YVO;GROSSMANN ADELBERT;NEUMANN SEBASTIAN;PARREN PAUL;REBERS FRANK;REGULA JOERG THOMAS;SCHUMACHER RALF;SEEBER STEFAN;STRACKE JAN OLAF;STUBENRAUCH KAY-GUNNAR;VAN DE WINKEL JAN;VAN VUGT MARTINE;VEREECKEN-VERPLOEGEN SANDRA |
| 分类号 |
A61K39/395;A61P11/06;A61P37/02;C07H21/00;C07K16/00;C12N1/00;C12N5/10;C12N15/63;C12P21/02 |
主分类号 |
A61K39/395 |
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