<p>Methods for screening for compounds that inhibit neurodegeneration are presented. Shedding of APP can be a useful marker for neurodegeneration and compounds that inhibit shedding of APP are useful as inhibitors of neurodegeneration. Such compounds may be useful in treatment and/or prevention of various neurological diseases, disorders and neuronal damage and may enhance growth, regeneration or survival of mammalian neuronal cells or tissue.</p>
申请公布号
WO2010096470(A4)
申请公布日期
2011.04.14
申请号
WO2010US24458
申请日期
2010.02.17
申请人
GENENTECH, INC.;NIKOLAEV, ANATOLY;PINKSTON-GOSSE, JULIE;TESSIER-LAVIGNE, MARC
发明人
NIKOLAEV, ANATOLY;PINKSTON-GOSSE, JULIE;TESSIER-LAVIGNE, MARC