发明名称 COMPOUNDS FOR THE MODULATION OF BETA-CATENIN EXPRESSION
摘要 The invention relates to oligomer compounds (oligomers), which target beta-catenin mRNA in a cell, leading to reduced expression of beta-catenin. Reduction of beta-catenin expression is beneficial for a range of medical disorders, such as hyperproliferative disorders, such as cancer. The invention provides therapeutic compositions comprising oligomers and methods for modulating the expression of beta-catenin using said oligomers, including methods of treatment.
申请公布号 US2011086902(A1) 申请公布日期 2011.04.14
申请号 US20100874668 申请日期 2010.09.02
申请人 SANTARIS PHARMA A/S;ENZON PHARMACEUTICALS, INC. 发明人 WORM JESPER
分类号 A61K31/7088;A61P35/04;C07H21/00;C12N5/09;C12N15/113 主分类号 A61K31/7088
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