Method to induce neovascular formation and tissue regeneration

摘要

The present invention refers to a method for inducing neovascular formation and/or tissue regeneration in a subject. The method comprises the administration of a plasmid vector comprising a nucleotide sequence encoding for the active site of the vascular endothelial growth factor (VEGF) or a polypeptide including the active site of VEGF. The method induces cell mitosis, myocardiogenesis, arteriogenesis, vasculogenesis and lymphangiogenesis in mammalian tissues.