DTCM glutarimide C-12 as iNOS and COX-2 inhibitor

摘要

The object of the present invention is to provide a pharmaceutical composition that inhibits expression of iNOS and COX-2 without inhibiting NF-ºB. The pharmaceutical composition that inhibits expression of iNOS and COX-2 without inhibiting NF-ºB contains DTCM glutarimide of the Formula (I) as an effective ingredient, thereby being able to inhibit nitric oxide (NO)production and prostaglandin production.