EFFICIENT ISOLATING METHOD OF ELLAGIC ACID FROM POMEGRANATE AND FUNCTIONAL COSMETICS COMPOSITION WITH ELLAGIC ACID EXTRACTS

摘要

PURPOSE: A functional cosmetic composition containing ellagic acid extract is provided to ensure anti-wrinkling and whitening effects. CONSTITUTION: A method for isolating ellagic acid from pomegranate comprises: a step of adding water, ethanol, methanol, ethyl acetate, n-hexane, or mixture thereof to dried and crushed pomegranate skin; a step of treating by 20-100 mHz ultrasonication at 25-45°C for 10 minutes to one hour; a step of adding 0.1-1M of HCl; a step of refluxing at 200°C for 1-3 hours; a step of adding aceonitrile to the extract; and a step of centrifuging the extract to separate supernatant. The cosmetic composition contains ellagic acid or ellagic acid extract. A pharmaceutical composition for preventing or treating atopy contains the ellagic acid or ellagic acid extract.