发明名称 |
FENOFIBRATE FORMULATION WITH ENHANCED ORAL BIOAVAILABILITY |
摘要 |
<p>The present invention provides a formulation of fenofibrate with enhanced oral bioavailability, simplicity of design and manufacture and absence of food effect. The formulation comprises fenofibrate dissolved in a lipophilic surfactant, with a hydrophilic surfactant optionally added. The formulation can be effectively used in the management and treatment of conditions such as hypertriglyceridemia, hypercholesterolemia and mixed dyslipidemia, and can also be effective at lower doses as compared to commercially available products. The invention additionally relates to the process of manufacture of the formulation and to dosage forms comprising the same.</p> |
申请公布号 |
EP2306989(A2) |
申请公布日期 |
2011.04.13 |
申请号 |
EP20090838194 |
申请日期 |
2009.06.26 |
申请人 |
PANACEA BIOTEC LIMITED |
发明人 |
JAIN, RAJESH;SINGH, SARABJIT;JAIN, NAVEEN;PUTHLI, SHIVANAND |
分类号 |
A61K9/48;A61K31/216 |
主分类号 |
A61K9/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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