| 发明名称 |
.ALPHA.-(N-SULPHONAMIDO)ACETAMIDE DERIVATIVES AS .BETA.-AMYLOID INHIBITORS |
| 摘要 |
There is provided a series of novel .alpha.-(N-sulfonamido)acetamide compounds of the Formula (I) wherein R, R1, R2 and R3 are defined herein, which are inhibitors of .beta.-amyloid peptide (.beta.-AP) production and are useful in the treatment of Alzheimer's Disease and other conditions affected by anti-amyloid activity.
|
| 申请公布号 |
CA2471099(C) |
申请公布日期 |
2011.04.12 |
| 申请号 |
CA20022471099 |
申请日期 |
2002.12.20 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
PARKER, MICHAEL F.;MCELHONE, KATHARINE E.;MATE, ROBERT A.;BRONSON, JOANNE J.;GAI, YONGHUA;BERGSTROM, CARL P.;MARCIN, LAWRENCE R.;MACOR, JOHN E. |
| 分类号 |
C07C311/19;A61K31/18;A61K31/192;A61K31/195;A61K31/197;A61K31/21;A61K31/216;A61K31/223;A61K31/24;A61K31/275;A61K31/277;A61K31/33;A61K31/341;A61K31/381;A61K31/40;A61K31/41;A61K31/415;A61K31/4164;A61K31/4184;A61K31/4196;A61K31/4245;A61K31/433;A61K31/44;A61K31/4402;A61K31/4406;A61K31/4409;A61K31/4439;A61K31/445;A61K31/4453;A61K31/4525;A61K31/4545;A61K31/455;A61K31/47;A61K31/472;A61K31/495;A61K31/497;A61K31/5375;A61K31/5377;A61K31/54;A61P25/28;A61P43/00;C07C237/04;C07C237/14;C07C317/32;C07C323/49;C07C323/60;C07D207/14;C07D207/32;C07D207/325;C07D211/14;C07D211/28;C07D211/42;C07D211/46;C07D211/58;C07D211/60;C07D213/40;C07D213/42;C07D213/61;C07D213/74;C07D213/81;C07D213/82;C07D215/06;C07D217/04;C07D217/06;C07D231/12;C07D233/64;C07D235/10;C07D235/14;C07D249/08;C07D257/04;C07D261/08;C07D271/06;C07D271/10;C07D277/28;C07D285/00;C07D285/01;C07D285/06;C07D285/12;C07D295/08;C07D295/088;C07D295/12;C07D295/13;C07D295/135;C07D295/14;C07D295/15;C07D295/18;C07D295/192;C07D295/20;C07D307/68;C07D333/20;C07D333/28;C07D401/04;C07D405/04;C07D413/04;C07D521/00 |
主分类号 |
C07C311/19 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
