| 摘要 |
FIELD: medicine, pharmaceutics. ^ SUBSTANCE: invention relates to field of medicine and deals with composition, which contains virus-like particle (VLP) and amyloid-beta peptide. Substance of invention includes application of construction, which consists of virus-like particle (VLP) structure, which is chemically stitched with fragment of A-1-42 peptide and its pharmaceutically acceptable salt for preparation of pharmaceutical composition, intended for treatment of dementia in patient by introduction of construction in dose 5-1000 mcg subcutaneously, every 4-8 weeks. Invention also includes combination, which includes construction on item 1, and at least, one agent, selected from group of medications, traditionally applied for treatment of Alzheimer's disease. ^ EFFECT: reduction of side effects. ^ 16 cl, 6 ex |
