发明名称 |
NOVEL CRYSTALLINE FORMS OF TRANS-7-OXO-6-(SULPHOOXY)-1,6-DIAZABICYCLO[3,2,1]OCTANE-2-CARBOXAMIDE SODIUM SALT |
摘要 |
<p>The present invention relates to novel crystalline forms of sodium salt of trans-7-oxo-6-(sulphooxy)-1,6-diazabicyclo[3,2,1]octane-2-carboxamide (e.g., NXL-104) thereof. The present invention relates to compositions comprising a crystalline form of sodium salt of trans-7-oxo-6-(sulphooxy)-1,6-diazabicyclo[3,2,1]octane-2-carboxamide (e.g., NXL-104) alone or in combination with an antibacterial agent (e.g., ceftaroline fosamil). Processes for the preparation of the crystalline forms and methods of treating bacterial infections by administering the crystalline forms alone or in combination with an antibacterial agent (e.g., ceftaroline fosamil) are also described.</p> |
申请公布号 |
CA2716914(A1) |
申请公布日期 |
2011.04.09 |
申请号 |
CA20102716914 |
申请日期 |
2010.10.08 |
申请人 |
FOREST LABORATORIES HOLDINGS LTD.;NOVEXEL SA |
发明人 |
DEDHIYA, MAHENDRA G.;BHATTACHARYA, SISIR;DUCANDAS, VERONIQUE;GIULIANI, ALEXANDRE;RAVAUX, VALERIE;BONNET, ALAIN;PRIOUR, ALAIN;SPARGO, PETER |
分类号 |
C07D471/08;A61K31/439;A61K31/675;A61P31/04 |
主分类号 |
C07D471/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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