| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a modified L-nucleic acid, use thereof, and a method for preparing the same. <P>SOLUTION: The modified L-nucleic acid includes an L-nucleic acid part and a non-L-nucleic acid part, wherein the L-nucleic acid part is conjugated with the non-L-nucleic acid part and the conjugation of the L-nucleic acid part with the non-L-nucleic acid part leads to a slowed elimination out of the organism, in comparison with an L-nucleic acid having the L-nucleic acid part alone, the L-nucleic acid part being a spiegelmer. The modified L-nucleic acid is used as a diagnostic agent or an additive for preparing a medicine. <P>COPYRIGHT: (C)2011,JPO&INPIT |
