发明名称 MOLECULAR PROBE FOR PANCREATIC ISLET IMAGING AND USE OF SAID PROBE
摘要 Provided is a molecular probe for pancreatic islet imaging. The molecular probe includes a polypeptide represented by formula (1) or a polypeptide having homology with said polypeptide. Z-HGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPPSX-NH2 (1) (Sequence No. 1) In formula (1), [X] is a lysine residue in which the side-chain amino groups are labeled by groups represented by formula (I). (I) In formula (I): A is an aromatic hydrocarbon group or an aromatic heterocyclic group; R1 is a substituent group containing 11C, 13N, 15O, 18F, 64Cu, 67Ga, 68Ga, 75Br, 76Br, 77Br, 99mTc, 111In, 123I, 124I, 125I or 131I; R2 is a hydrogen atom or a substituent group different from R1; and R3 is any of a bond, a C1-C6 alkylene group, or a C1-C6 oxyalkylene group.
申请公布号 WO2011040460(A1) 申请公布日期 2011.04.07
申请号 WO2010JP66940 申请日期 2010.09.29
申请人 KYOTO UNIVERSITY;ARKRAY, INC.;SAJI HIDEO;INAGAKI NOBUYA;TOYODA KENTARO;KIMURA HIROYUKI;HIRAO KONOMU;NAGAKAWA KENJI;MATSUDA HIROKAZU 发明人 SAJI HIDEO;INAGAKI NOBUYA;TOYODA KENTARO;KIMURA HIROYUKI;HIRAO KONOMU;NAGAKAWA KENJI;MATSUDA HIROKAZU
分类号 A61K51/00;G01T1/161 主分类号 A61K51/00
代理机构 代理人
主权项
地址