发明名称 |
COMPLEXES OF IL-15 AND IL-15RALPHA AND USES THEREOF |
摘要 |
The present invention relates to agents that modulate interleukin-15 (“IL-15”) signal transduction or function (“Therapeutic Agents”) and the use ol″ those agents to modulate immune function. The Therapeutic Agents target the interaction between IL-15 and its receptor and modulate IL-15-induced signal transduction. The Therapeutic Agents may be formulated with polymers, such as poly-&bgr;-1-♦4-N-acetylglucosamine. for administration to a human subject to modulate IL-15-mediated immune function.
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申请公布号 |
US2011081311(A1) |
申请公布日期 |
2011.04.07 |
申请号 |
US20080666052 |
申请日期 |
2008.06.27 |
申请人 |
PAVLAKIS GEORGE N;VOURNAKIS JOHN N;FELBER BARBARA K;FINKIELSZTEIN SERGIO |
发明人 |
PAVLAKIS GEORGE N.;VOURNAKIS JOHN N.;FELBER BARBARA K.;FINKIELSZTEIN SERGIO |
分类号 |
A61K38/20;A61K35/12;A61K39/395;C12N5/10;C12N15/63 |
主分类号 |
A61K38/20 |
代理机构 |
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