VASOACTIVE PEPTIDE AND DERIVATIVES THEREOF

摘要

The present invention is in the field of pharmacological active peptides and peptide analogs which can be used as therapeutics to treat diseases characterized by dysfunctional vascular physiology. The peptides modulate gene expression in blood vessel cells and they regulate vessel tonus thus influencing blood pressure and the function of main cardiovascular organs like kidney, heart and lung as well. The therapeutic mode of action of the vasoactive peptides results in amelioration of organ blood perfusion and antagonism of cellular degenerative processes within these organs. These modes of action of the peptides result in organ-protective effects and ameliorate the health conditions of patients suffering from cardiovascular diseases.