发明名称 |
ULTRA-NANOCRYSTALLINE DIAMOND AS A BIOMATERIAL FOR ENHANCING PROLIFERATION AND DIFFERENTIATION OF NEURAL STEM CELLS |
摘要 |
Compositions for promoting growth and/or differentiation of a stem cell are disclosed. The composition comprises: a) a diamond film; b) a stem cell cultured on the diamond film; and c) a medium bathing the stem cell. The stem cell may be a mammalian neural stem cell and the diamond film may comprise a hydrogen-terminated or an oxygen-terminated surface. The hydrogen-terminated surface promotes proliferation and differentiation of a neural stem cell into neurons, and the oxygen-terminated surface promotes a neural stem cell to proliferate and differentiate into oligodendrocytes.
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申请公布号 |
US2011081395(A1) |
申请公布日期 |
2011.04.07 |
申请号 |
US20090573878 |
申请日期 |
2009.10.05 |
申请人 |
NATIONAL HEALTH RESEARCH INSTITUTES;NATIONAL TSING HUA UNIVERSITY |
发明人 |
CHIU ING-MING;CHEN YING-CHIEH;LEE DON-CHING;TAI NYAN-HWA |
分类号 |
A61F2/00;A61K35/12;C12N5/079 |
主分类号 |
A61F2/00 |
代理机构 |
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