发明名称 PYRIDONE COMPOUNDS
摘要 [Problems] A useful compound which can be used as a pharmaceutical, in particular, an agent for treating peripheral arterial occlusive disease is provided. [Means for Solution] The present inventors have conducted extensive studies on EP4 receptor agonists, and as a result, have found that a novel pyridone compound, in which a group having an acidic group is substituted at the 1-position of the pyridone ring, the 6-position is bonded with an aromatic ring group via a linking part, and the linking part contains a nitrogen atom, has an excellent EP4 receptor agonistic action, thereby completing the present invention. Since the compound of the present invention has an excellent EP4 receptor agonistic action, it is useful as a pharmaceutical, in particular, as an agent for treating peripheral arterial occlusive disease.
申请公布号 US2011082133(A1) 申请公布日期 2011.04.07
申请号 US20090999379 申请日期 2009.06.16
申请人 KAMIKUBO TAKASHI;MIURA MASANORI;OKUDA TAKAO;MAKI KEISUKE;HIRAYAMA FUKUSHI;MORITOMO AYAKO;KOMIYA YURIKO;MATSUURA KEISUKE;IBUKA RYOTARO 发明人 KAMIKUBO TAKASHI;MIURA MASANORI;OKUDA TAKAO;MAKI KEISUKE;HIRAYAMA FUKUSHI;MORITOMO AYAKO;KOMIYA YURIKO;MATSUURA KEISUKE;IBUKA RYOTARO
分类号 A61K31/5415;A61K31/4412;A61K31/4439;A61K31/444;A61K31/4725;A61P9/10;C07D211/72;C07D401/06;C07D417/06;C07D417/12 主分类号 A61K31/5415
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