发明名称 |
Multiparticulates of preferably an opioid, and method of manufacturing using extrusion |
摘要 |
<p>Extrusion of a mix containing a pharmaceutically active agent can be achieved using a plasticising excipient in an amount sufficient to act as plasticiser and also act as lubricant, thereby avoiding the need for inclusion of a lubricant. The invention provides multiparticulates with controlled release properties, substantially free of lubricant.</p> |
申请公布号 |
AU2005278919(B2) |
申请公布日期 |
2011.04.07 |
申请号 |
AU20050278919 |
申请日期 |
2005.08.31 |
申请人 |
EURO-CELTIQUE S.A. |
发明人 |
HARJIT TAMBER;GEOFFREY GERARD HAYES;VINCENZO MARTINELLI;STEVE WHITELOCK;MALCOLM WALDEN;HASSAN MOHAMMAD |
分类号 |
A61K9/14;A61K9/16;A61K31/485;B29C47/60 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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