| 发明名称 |
Use of Panton-Valentine Leukocidin for treating and preventing staphylococcus infections |
| 摘要 |
<p>The present invention relates to compositions and methods for treating <Italic>Staphylococcus aureus</Italic> (<Italic>S. aureus</Italic>) infections. In particular, the present invention provides vaccines comprising a Panton-Valentine Leukocidin (PVL) antigen, antibodies which bind a PVL antigen and compositions containing the same, methods of making such compositions and methods for treating <Italic>S</Italic>. <Italic>aureus</Italic> infections, including those that are community acquired methicillin-resistant infections. The present invention also provides PVL antibodies, including PVL antibodies specific for a single PVL subunit, and PVL antigens, including conjugated and mutated PVL antigens.</p> |
| 申请公布号 |
EP2289938(A3) |
申请公布日期 |
2011.04.06 |
| 申请号 |
EP20100180402 |
申请日期 |
2006.06.13 |
| 申请人 |
GLAXOSMITHKLINE BIOLOGICALS S.A. |
发明人 |
TAYLOR, KIMBERLY LOUISE;FATTOM, ALI IBRAHIM |
| 分类号 |
C07K16/12;A61K39/085;A61K39/395;A61P31/04;C07K14/31 |
主分类号 |
C07K16/12 |
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