发明名称 BCL-2 PROTEIN EXPRESSOR, APOPTOSIS INHIBITOR AND PREVENTIVE FOR UV-DNA DAMAGE IN EPIDERMAL CELLS
摘要 An object of the present invention is to provide an apoptosis inhibiting agent which inhibits apoptosis of a cell having a DNA which is directly or indirectly damaged with ultraviolet-rays or the like, enhances the tissue restoring property of a cell, can be added to various drugs, and can be expected to be widely applied. An apoptosis inhibiting agent for an epidermal cell, containing a water and ethanol-soluble glycyrrhiza extract as an active ingredient. The apoptosis inhibiting agent has an anti-apoptotic factor due to expression of BLC-2 protein, and has the property of preventing a DNA damage due to ultraviolet-rays. The agent alleviates the DNA damage of an epidermal cell due to ultraviolet exposure and, moreover, does not abnormally or adversely affect a normal skin cell.
申请公布号 EP2305280(A1) 申请公布日期 2011.04.06
申请号 EP20080764599 申请日期 2008.05.23
申请人 NISHIHARA CO., LTD. 发明人 TAKITA, MASAO
分类号 A61K8/97;A61K8/34;A61Q17/04;A61Q19/00 主分类号 A61K8/97
代理机构 代理人
主权项
地址