发明名称 |
ORALLY ADMINISTERABLE VACCINE FOR YERSINIA PESTIS |
摘要 |
Disclosed herein is the successful expression of the plague F1-V fusion antigen in chloroplasts. Parenteral and/or oral administration of chloroplast produced antigens effectively elicit protective immune responses in vivo. Disclosed herein is the first report of a plant-derived oral vaccine that protected animals from live Y. pestis challenge, bringing the likelihood of lower-cost vaccines closer to reality. |
申请公布号 |
EP2303296(A2) |
申请公布日期 |
2011.04.06 |
申请号 |
EP20090814927 |
申请日期 |
2009.05.27 |
申请人 |
UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. |
发明人 |
DANIELL, HENRY |
分类号 |
A61K36/28;A61K38/16;A61K39/00;A61P31/04 |
主分类号 |
A61K36/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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