发明名称 |
Stabilized amorphous forms of imatinib mesylate |
摘要 |
The invention relates to the stabilized amorphous form of the methanesulfonic acid addition salt of 4-(4-methylpiperazin-1-ylmethyl)-N-[4-methyl-3-(4-(pyridin-3-yl)-pyrimidin-2-ylamino)-phenyl]-benzamide, pharmaceutical compositions such as capsules or tablets containing this form, the use of such form in diagnostic methods or, preferably, for the therapeutic treatment of warm-blooded animals, especially humans, and the use of formulation principles stabilizing the amorphous form of Imatinib mesylate as an intermediate for the preparation of pharmaceutical compositions. |
申请公布号 |
EP2305263(A1) |
申请公布日期 |
2011.04.06 |
申请号 |
EP20100178116 |
申请日期 |
2007.06.07 |
申请人 |
NOVARTIS AG |
发明人 |
GONCALVES, ELISABETE;KALB, OSKAR;MUTZ, MICHAEL;WIRTH, WOLFGANG |
分类号 |
A61K31/506;A61K9/16;A61P35/02 |
主分类号 |
A61K31/506 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|