发明名称 |
Simultaneous quantification of nucleic acids in diseased cells |
摘要 |
A process for assessing mitochondrial toxicity of a compound that includes contacting nucleic acids from a host with an amplification reaction mixture that contains at least two primers that provide detectable signals, wherein: a first primer provides a first detectable signal upon amplification of a host mitochondrial nucleic acid; a second primer provides a second detectable signal upon amplification of a host nuclear nucleic acid; and comparing the first and second detectable signals.
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申请公布号 |
US7919247(B2) |
申请公布日期 |
2011.04.05 |
申请号 |
US20070949162 |
申请日期 |
2007.12.03 |
申请人 |
PHARMASSET, INC. |
发明人 |
STUYVER LIEVEN;OTTO MICHAEL J. |
分类号 |
C12N15/09;C12Q1/68;C07H19/048;C07H19/06;C07H19/10;C07H19/16;C07H19/20;C07H21/04;C12P19/34;C12Q1/70 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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