发明名称 |
Method of inhibiting prostate cancer cell proliferation |
摘要 |
The present invention relates to a method of inhibiting or reducing the proliferation of prostate cancer cells, such as androgen independent prostate cancer (AIPC) cells, the method comprising administering to the cells a PLA2 inhibitor. In one embodiment the PLA2 inhibitor is a conformationally constrained molecule derived from a peptide consisting essentially of amino acid residues 70-74 of a human sPLA2-IIA protein, or the equivalent residues in other sPLA2 proteins.
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申请公布号 |
US7919458(B2) |
申请公布日期 |
2011.04.05 |
申请号 |
US20030517256 |
申请日期 |
2003.06.10 |
申请人 |
SCOTT, KIERAN, FRANCIS |
发明人 |
GRAHAM GARRY GEORGE;DONG QIHAN |
分类号 |
A61K38/12;A61K31/00;A61K31/16;A61K31/40;A61K31/445;A61K31/505;A61K35/36;A61K38/43;A61K38/46;A61K47/10;A61K47/14;A61P35/00;A61P35/04;C12Q1/68;G01N33/574 |
主分类号 |
A61K38/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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