发明名称 |
Increasing hybridization efficiencies |
摘要 |
Aspects of the disclosure are generally directed to probes and probe compositions for detecting or quantifying a target. One aspect provides a method for selectively hybridizing a probe to a polynucleotide by contacting a sample containing a first and second polynucleotide with a probe. The probe includes a number of nucleotides complementary to the first or second polynucleotide in the region of mismatch between the first and second polynucleotides. Another aspect provides arrays including the disclosed probes and methods of using the arrays and the probes.
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申请公布号 |
US7919239(B2) |
申请公布日期 |
2011.04.05 |
申请号 |
US20050173078 |
申请日期 |
2005.07.01 |
申请人 |
AGILENT TECHNOLOGIES, INC. |
发明人 |
WANG HUI |
分类号 |
C12Q1/68;C07H21/02;C07H21/04;C12M1/34;C12M3/00;C12P19/34 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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