发明名称 USE OF A QUINOLONE DERIVATIVE CONTAINING 7-(4-AMINOMETHYL-3-OXIME) PYRROLIDINE GROUP THAT IS CAPABLE OF INDUCING GRANULOCYTE COLONY STIMULATING FACTOR FOR TREATMENT OF NEUTROPENIA AND RECOVERY OF HEMATOPOIESIS
摘要 PURPOSE: A quinolones antibiotics having 7-(4-aminomethyl-3-oxime)pyrolidine substituent is provided to treat neutropenia. CONSTITUTION: A therapeutic agent for neutropenia contains effective amount of compound of chemical formula 1, pharmaceutically acceptable salt thereof, solvate containign hydrate, ester, steriochemical isomer, or precursor as an active ingredient. The compound of chemical formula 1 is gemifloxacin. The neutropenia is caused from a patient with adult acute myeoloid leukemia, who treated by chemical therapy. A therapeutic agent for primary marrow failure contains effective amount of compound of chemical formula 1, pharmaceutically acceptable salt thereof, solvate containing the hydrate, ester, steriochemical isomer or precursor.
申请公布号 KR20110034566(A) 申请公布日期 2011.04.05
申请号 KR20100093471 申请日期 2010.09.27
申请人 LG LIFE SCIENCES LTD. 发明人 PARK, HEE DONG;CHOI, JU HYUN;PARK, JUNG GYU
分类号 A61K31/4375;A61P37/00 主分类号 A61K31/4375
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