发明名称 |
ANTI P-SELECTIN GLYCOPROTEIN LIGAND 1 (PSGL-1) ANTIBODIES AND ANTIGEN-BINDING FRAGMENTS THEREOF |
摘要 |
Compounds that bind to P-Selectin Glycoprotein 1 (PSGL-1) on the surface of T cells or natural killer (NK) cells can be used to induce T cell or NK cell depletion and/or to induce T cell or NK cell apoptosis. The compounds and methods of the invention can be used to control unwanted T cell- or NK cell-mediated immune responses in conditions such as autoimmune diseases, transplant rejection, and allergic diseases. |
申请公布号 |
IL210557(D0) |
申请公布日期 |
2011.03.31 |
申请号 |
IL20110210557 |
申请日期 |
2011.01.11 |
申请人 |
ABGENOMICS COOPERATIEF U.A.;ABGENOMICS CORPORATION |
发明人 |
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分类号 |
G01N33/48;A61K;A61K39/395;A61K45/00;A61P35/00;A61P37/06;A61P37/08;A61P43/00;C07K16/28;C12Q1/02;G01N33/15;G01N33/50;G01N33/53;G01N33/577 |
主分类号 |
G01N33/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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