发明名称 |
DETECTION OF ANALYTES VIA NANOPARTICLE-LABELED SUBSTANCES WITH ELECTROMAGNETIC READ-WRITE HEADS |
摘要 |
A first set of antibodies are bonded to a substrate, and are exposed to and bonded with target antigens. A second set of antibodies are bonded to nanoparticles, and the nanoparticle labeled antibodies are exposed to the targeted antigens. An electromagnetic write-head magnetizes the nanoparticles, and then a read-sensor detects the freshly magnetized nanoparticles. The substrate comprises a flexible film or a Peltier material to allow selective heating and cooling of the antigens and antibodies. Nanoparticles of different magnetic properties may be selectively paired with antibodies associated with different antigens to allow different antigens to be detected upon a single scan by the read-sensor.
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申请公布号 |
US2011076670(A1) |
申请公布日期 |
2011.03.31 |
申请号 |
US20100888388 |
申请日期 |
2010.09.22 |
申请人 |
INTERNATIONAL BUSINESS MACHINES CORPORATION |
发明人 |
BODAY DYLAN JOSEPH;RANDALL LEE CURTIS;SCHWARTZ STEPHEN LEONARD;TOPOL ANNA W.;WINARSKI DANIEL JAMES |
分类号 |
G01N33/53;B01J19/00;C12Q1/70 |
主分类号 |
G01N33/53 |
代理机构 |
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地址 |
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