| 摘要 |
<p>Compds. (I) and their acid addition salts. Ar - O - CH2 - CHOH - CH2 - NH - CHMe3 (I) (where Ar is 5-6, 6-7 or 7-8 dihydronaphthalene) are beta-adrenergic blocking agents and are pred. (a) from iso-PrNH2 and a compd. ArO.CH2CHX.CHY.Z (where Z =H and X and Y together = O or Z= Hal X = OH and Y=H) (b) from isoPr Hal and a compd. ArOCH2CHOH-CH2.NH2 (c) by alkaline hydrolysis of a compd. and (d) from ArOM and Hal-CH2-CHOH-CH2NH-isoPr. (where M= monovalent cation).</p> |
