发明名称 |
CRYSTALLINE METHYLTHIONINIUM CHLORIDE HYDRATES |
摘要 |
Three dihydrate forms B, C and D and a monohydrate form E of methylthloninium chloride (methylene blue) are described. Forms B, C, D and E can be prepared under controlled humidity and temperature from methylthioninium chloride with higher water content or conversion of a hydrate. The hydrates can be incorporated in pharmaceutical compositions.
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申请公布号 |
CA2773305(A1) |
申请公布日期 |
2011.03.31 |
申请号 |
CA20102773305 |
申请日期 |
2010.09.23 |
申请人 |
WISTA LABORATORIES LTD. |
发明人 |
HILFIKER, ROLF;RAGER, TIMO |
分类号 |
C07D279/18;A61K31/5415;A61P25/28;A61P31/12;A61P35/00 |
主分类号 |
C07D279/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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