<p>A method of detecting a risk of a pregnant female mammal developing pre-eclampsia or a complication linked thereto, or of a fetus of the pregnant female mammal developing a fetal or neonatal deficiency linked to maternal pre-eclampsia, comprises detecting the level of a VEGFxxxb in a sample from the pregnant female mammal at less than about 24 weeks of gestation and comparing the detected level with a reference level. A reduced level in the sample from the pregnant female mammal is indicative of a risk of the pregnant female mammal developing pre-eclampsia or a complication linked thereto or of the fetus developing the fetal or neonatal deficiency linked to maternal pre-eclampsia.</p>
申请公布号
WO2011036429(A1)
申请公布日期
2011.03.31
申请号
WO2009GB51263
申请日期
2009.09.25
申请人
THE UNIVERSITY OF BRISTOL;BATES, DAVID, OWEN;BILLS, VICTORIA, LOUISE;HARPER, STEPHEN, JAMES;QIU, YAN
发明人
BATES, DAVID, OWEN;BILLS, VICTORIA, LOUISE;HARPER, STEPHEN, JAMES;QIU, YAN