发明名称 |
DETERMINATION OF KIR HAPLOTYPES ASSOCIATED WITH DISEASE |
摘要 |
Disclosed is a method of determining KIR genotypes for one or more individuals in parallel, the method comprising: for each individual, amplifying the polymorphic exon sequences of the KIR genes, pooling the KIR amplicons, performing emulsion PCR followed by pyrosequencing in parallel to determine all the amplicon sequences present in the individual to determine which KIR alleles are present in the individual. |
申请公布号 |
WO2011035870(A1) |
申请公布日期 |
2011.03.31 |
申请号 |
WO2010EP05721 |
申请日期 |
2010.09.17 |
申请人 |
ROCHE DIAGNOSTICS GMBH;F. HOFFMANN-LA ROCHE AG |
发明人 |
BENTLEY, GORDON;ERLICH, HENRY A.;GOODRIDGE, DAMIAN;LADNER, MARTHA;TRACHTENBERG, ELIZABETH |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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