发明名称 PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION
摘要 <p>An oral pharmaceutical composition characterized in that it consists of a suspension of a platinum complex of general formula I, wherein A and A′independently of one another are an NH3 group or an amino or diamino group containing 1 to 18 carbon atoms, B and B′independently of one another are a halogen atom or a hydroxy group or are an—O—C(O)—R or an—O—C(O)—R′group wherein R and R′independently of one another are hydrogen atom, an alkyl, alkenyl, aryl, aralkyl, alkylamino or alkoxy group which groups contain 1 to 10 carbon atoms, or functional derivatives of these groups, X and X′independently of one another are a halogen atom or a monocarboxylate group containing 1 to 20 carbon atoms, or X and X′together form a dicarboxylate group containing 2 to 20 carbon atoms, in at least one pharmaceutically acceptable vegetable, animal, mineral, synthetic or semisynthetic oil and/or in at least one pharmaceutically acceptable vegetable, animal, mineral, synthetic or semisynthetic oily substance, in which suspension the content of the platinum complex of general formula I is 0.5 to 50% by weight based on the total weight of the composition, and which suspension optionally contains at least one pharmaceutically acceptable excipient.</p>
申请公布号 SI2034957(T1) 申请公布日期 2011.03.31
申请号 SI20070030418T 申请日期 2007.06.20
申请人 PLIVA-LACHEMA A.S. 发明人 FRANC ALES;SOVA PETR
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