Antibodies against amyloid-beta peptide

摘要

A therapeutic antibody which binds beta-amyloid peptide comprising the following CDRs: CDRH1: DNGMA (SEQ ID NO:1) CDRH2: FISNLAYSIDYADTVTG (SEQ ID NO:2) CDRH3: GTWFAY (SEQ ID NO:3); and CDRL1: RVSQSLLHSNGYTYLH (SEQ IDNO:4) CDRL2: KVSNRFS (SEQ ID NO: 5) CDRL3: SQTRHVPYT (SEQ ID NO: 6) The antibody can be used for treating disease or disorders characterised by elevated beta-amyloid levels or beta-amyloid deposits.