发明名称 |
ANTI-PRION PROTEIN ANTIBODY FRAGMENT |
摘要 |
The application relates to an antibody, antibody fragment or derivative thereof which specifically recognizes a prion protein and which comprises a complementarity determining region (CDR), a retro-inverso D-peptide of said CDR and/or an anti-idiotypic antibody, antibody fragment or derivative thereof which recognizes said CDR. The application further concerns a nucleic acid molecule encoding said antibody, antibody fragment or derivative thereof as well as a method for generating an antibody, antibody fragment or derivative thereof that specifically recognizes a prion protein, wherein an antibody that recognizes a specific domain of the prion protein is generated, an antigen-specific amino acid sequence is isolated from said antibody, and an anti-idiotypic antibody, antibody fragment or derivative thereof, which recognizes said antigen-specific amino acid sequence, is generated. |
申请公布号 |
EP2300499(A1) |
申请公布日期 |
2011.03.30 |
申请号 |
EP20090765609 |
申请日期 |
2009.06.16 |
申请人 |
KORTH, CARSTEN;STITZ, LOTHAR;PETSCH, BENJAMIN;MUELLER-SCHIFFMANN, ANDREAS |
发明人 |
LELIVELD, SIRIK, RUTGER;KORTH, CARSTEN;STITZ, LOTHAR;PETSCH, BENJAMIN;MÜLLER-SCHIFFMANN, ANDREAS |
分类号 |
C07K16/28;A61K39/395;A61P25/28;C07K7/08;C12N15/13 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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