摘要 |
<p>Solubilisers for phenoxyacetic acid amide narcotics comprise water-soluble, non-ionic surfactants, esp. sugar esters or ethylene oxide derivs. of fatty acids, fatty alcohols, fatty oils and fatty acid esters of sorbitan. Specific cpds. Cremophor EL (R) (ethoxylated castor oil) Oleyl polyglycol ether Polyethylene oxide sorbitan monooleate Polyhydroxyethylene stearate Saccharose monolaurate Claimed Cremophor EL (R) to solubilise 2-methoxy-4-allyphenoxyacetic acid-N:N -diethylamide, 3-methoxy-4-N:N-diethyl-carbamido-methoxyphenyl-acetic acid n-propyl ester and 2-methoxy-4-allyl-phenoxyacetic acid-N-ethyl-N-ethoxy amide. Narcotics for intravenous injection. Good intravenous compatibility - lack of irritation of vein wall.</p> |