GENERATION OF HEAVY-CHAIN ONLY ANTIBODIES IN TRANSGENIC ANIMALS
摘要
The present invention relates to a method for the generation of VH heavy chain-only antibodies in a transgenic non-human mammal. In particular, the present invention relates to a method for the production of a VH heavy chain- only antibody in a transgenic nonhuman mammal comprising the step of expressing more than one heterologous VH heavy chain locus in that mammal. No suitable figure
申请公布号
SG169348(A1)
申请公布日期
2011.03.30
申请号
SG20110005378
申请日期
2007.01.25
申请人
ERASMUS UNIVERSITY MEDICAL CENTER ROTTERDAM
发明人
GROSVELD, FRANKLIN, GERARDUS;JANSSENS, RICHARD, WILHELM