| 摘要 |
Glycans are identified which have high affinity for C. difficile toxin A. They share one of two saccharide backbones and may have additional side chains. The backbones are galactose-&bgr;1-3 N-acetyl-D-glucosamine-&bgr;-1-3-galactose-&bgr;-1-4-N-acetyl-D-glucosamine and galactose-α-1-3-galactose-&bgr;-1-4-N-acetyl-D-glucosamine. The ligands may be used therapeutically, prophylactically, and diagnostically.
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