发明名称 |
Opioid agonist formulations with releasable and sequestered antagonist |
摘要 |
Disclosed are oral dosage forms, comprising (i) a therapeutically effective amount of an opioid agonist; (ii) an opioid antagonist in releasable form; and (iii) a sequestered opioid antagonist which is not released when the dosage form is administered intact, and methods thereof.
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申请公布号 |
US7914818(B2) |
申请公布日期 |
2011.03.29 |
申请号 |
US20020213919 |
申请日期 |
2002.08.06 |
申请人 |
PURDUE PHARMA L.P. |
发明人 |
BREDER CHRISTOPHER;WRIGHT CURTIS;OSHLACK BENJAMIN |
分类号 |
A61K9/22;A61K9/32;A61K9/16;A61K9/20;A61K9/50;A61K31/135;A61K31/44;A61K31/445;A61K31/485;A61K45/06;A61P25/04;A61P25/36;A61P43/00 |
主分类号 |
A61K9/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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