发明名称 |
COMPOUNDS HAVING TAFIA INHIBITORY ACTIVITY |
摘要 |
The present invention provides compounds having superior TAFIa inhibitory activity. They are dihydroimidazoquinoline compounds represented by the following formula (I) or pharmaceutically acceptable salts thereof: (I) wherein R is a hydrogen atom or a C1-10 alkyl group; R1 is a hydrogen atom, a C1-10 alkyl group, a C3-8 cycloalkyl group or a substituent having the structure represented by the following formula Ia or Ib: (Ia) (Ib) where R3 is a C1-6 alkyl group; R4 is a C1-6 alkyl group, a C3-8 cycloalkyl group, or a benzyl group; and R2 is a hydrogen atom or a substituent having the structure represented by the following formula Ic or Id:(Ic) (Id)
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申请公布号 |
CA2773125(A1) |
申请公布日期 |
2011.03.24 |
申请号 |
CA20102773125 |
申请日期 |
2010.09.17 |
申请人 |
TAISHO PHARMACEUTICAL CO., LTD. |
发明人 |
AMADA, HIDEAKI;MATSUDA, DAISUKE;BOHNO, AYAKO |
分类号 |
C07D471/04;A61K31/4745;A61P1/04;A61P3/04;A61P7/02;A61P9/10;A61P11/00;A61P11/16;A61P13/12;A61P19/02;A61P31/04;A61P35/00;A61P43/00 |
主分类号 |
C07D471/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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