摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide a method for culturing a hematopoietic stem cell by which the hematopoietic stem cell for transplanting the hematopoietic stem cell can be produced. <P>SOLUTION: The method for culturing the hematopoietic stem cell includes a step of culturing the hematopoietic stem cell in the presence of SFRP-2 protein. For that purpose, the SFRP-2 protein may be added to a culture medium or the SFRP-2 protein expression vector may be introduced into the hematopoietic stem cell. In either of the methods for culturing, the concentration of the SFRP-2 protein in the culture medium may be≥0.1μg/mL and≤10μg/mL. The resultant cell is used for transplanting the hematopoietic stem cell. <P>COPYRIGHT: (C)2011,JPO&INPIT</p> |